Tuberculosis (TB) Fact Sheets- Tuberculin Skin Testing (2024)

Skin test interpretation depends on two factors:

  • Measurement in millimeters of the induration
  • Person’s risk of TB infection or the risk of progression to TB disease if infected
Classification of the Tuberculin Skin Test Reaction
Classification of the Tuberculin Skin Test Reaction
An induration of 5 or more millimeters is considered positive in

-People living with HIV

-A recent contact of a person with infectious TB disease

– People with chest x-ray findings suggestive of previous TB disease

-People with organ transplants

-Other immunosuppressed people (e.g., patients on prolonged therapy with corticosteroids equivalent to/greater than 15 mg per day of prednisone or those taking TNF-a antagonists)

An induration of 10 or more millimeters is considered positive in

-People born in countries where TB disease is common, including Mexico, the Philippines, Vietnam, India, China, Haiti, and Guatemala, or other countries with high rates of TB

-People who abuse drugs

-Mycobacteriology laboratory workers

-People who live or work in high-risk congregate settings (e.g., nursing homes, homeless shelters, or correctional facilities)

-People with certain medical conditions that place them at high risk for TB (e.g., silicosis, diabetes mellitus, severe kidney disease, certain types of cancer, and certain intestinal conditions)

-People with a low body weight (<90% of ideal body weight)

-Children younger than 5 years of age

-Infants, children, and adolescents exposed to adults in high-risk categories

An induration of 15 or more millimeters is considered positive in

-People with no known risk factors for TB

Tuberculosis (TB) Fact Sheets- Tuberculin Skin Testing (2024)

FAQs

Tuberculosis (TB) Fact Sheets- Tuberculin Skin Testing? ›

A Tuberculosis (TB) Skin Test is used to test for TB infection. You need a TB skin test if you have spent time with someone sick with active TB disease or if you are at risk of developing TB disease if infected with TB.

What is the fact sheet of tuberculosis? ›

TB usually affects the lungs. The bacteria are put into the air when a person with TB of the lung coughs, sneezes, laughs, or sings. TB can also affect other parts of the body, such as the brain, the kidney, or the spine. Tuberculosis is a disease that can be cured if treated properly.

What is a tuberculin skin test for tuberculosis? ›

Tuberculin skin tests (TST) are administered to detect the presence of Mycobacterium tuberculosis, the bacterium that causes tuberculosis (TB). The terms Mantoux, TB skin test, tuberculin skin test, and PPDs are often used interchangeably.

What is the difference between a TB test and a TB skin test? ›

Want a better test for TB infection? Then you want a TB blood test! The TB blood test is more specific than a TB skin test (less likely to cause a false positive) and it requires only one visit, while a TB skin test may require several visits (four visits over a 10 to 21 day period for a two-step test).

What does skin look like if TB test is positive? ›

Results. Redness alone at the skin test site usually means you haven't been infected with TB bacteria. A firm red bump may mean you have been infected with TB bacteria at some time. The size of the firm bump (not the red area) is measured 2 to 3 days after the test to find out the result.

What are 4 facts about tuberculosis? ›

Tuberculosis (TB) is an infectious disease that most often affects the lungs and is caused by a type of bacteria. It spreads through the air when infected people cough, sneeze or spit. Tuberculosis is preventable and curable. About a quarter of the global population is estimated to have been infected with TB bacteria.

What is the full information about tuberculosis? ›

Tuberculosis (TB) is a serious illness that mainly affects the lungs. The germs that cause tuberculosis are a type of bacteria. Tuberculosis can spread when a person with the illness coughs, sneezes or sings. This can put tiny droplets with the germs into the air.

How accurate is the TB skin test? ›

TB skin: Subjective results. Requires 2 separate appointments and manual results. Sensitivity of 79% and specificity of 97% with specificity being as low as 59% in BCG-vaccinated patients (high false positive).

Can you have a positive TB skin test and not have TB? ›

Some persons may react to the TST even though they are not infected with M. tuberculosis. The causes of these false-positive reactions may include, but are not limited to, the following: Previous TB vaccination with the bacille Calmette-Guérin (BCG) vaccine.

How long are TB skin tests good for? ›

How long is the test valid? A negative test is valid for 2 years and must not expire at any time during the semester.

How do you know if TB skin test is negative? ›

The test is "negative" if there is no bump (or only a very small bump) at the spot where the fluid was injected. A negative TB skin test usually means that you don't have TB. In some situations, you may need to have another TB skin test later.

How do you read a tuberculosis skin test? ›

If you have an Mtb infection, the skin around the injection site should start to swell and harden within 48 to 72 hours . This bump, or induration, may also change color. But the induration's size, not the color, will determine your results. An induration of less than 5 millimeters (mm) is a negative result.

What not to do before a TB test? ›

You don't any special preparations for TB skin test or a TB blood test.

What are some historical facts about tuberculosis? ›

TB in humans can be traced back to 9,000 years ago in Atlit Yam, a city now under the Mediterranean Sea, off the coast of Israel. Archeologists found TB in the remains of a mother and child buried together. The earliest written mentions of TB were in India (3,300 years ago) and China (2,300 years ago).

What are some facts about pulmonary TB? ›

Pulmonary TB is characterised by a cough with sputum (sometimes with blood), chest pain, shortness of breath and a general feeling of weakness. Extrapulmonary TB can affect any part of the body and symptoms are site-related. The BCG (Bacillus Calmette–Guérin) vaccine provides partial protection against TB.

How long does tuberculosis last? ›

The main treatment for tuberculosis (TB) is to take antibiotics for at least 6 months. If TB has spread to your brain, spinal cord or the area around your heart, you may also need to take steroid medicine for a few weeks.

What is the death rate of tuberculosis? ›

There is also considerable variation in the case fatality ratio (CFR) i.e. the estimated proportion of people who develop TB that die from the disease (Fig. 2.2. 13). Globally, the CFR was 15% in 2021, up from 14% in 2019.

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